CL264

Names

[ CAS No. ]:
1510712-69-2

[ Name ]:
CL264

Biological Activity

[Description]:

CL264 is a TLR7-specific agonist for innate immune signals research[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Inflammation/Immunology

[Target]

TLR7

[In Vitro]

Toll like receptors (TLRs) are the best-studied class of receptors that are essential players in the detection of a range of lipid-, protein-, nucleic acid-based PAMPs. TLR7 is expressed predominantly in plasmacytoid dendritic cells (pDCs), macrophages and B cells. Many TLR7 modulators are interferon inducers, anti-cancer agents, anti-infectious agents, therapeutic agents for immunological diseases and vaccine adjuvants[1].

[References]

[1]. Butterfield JSS, et al. TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer. Hum Gene Ther Methods. 2019 Jun;30(3):81-92.

Chemical & Physical Properties

[ Density]:
1.427±0.06 g/cm3(Predicted)

[ Molecular Formula ]:
C₁₉H₂₃N₇O₄

[ Molecular Weight ]:
413.43

[ Storage condition ]:
2-8°C

CL264

Names

Biological Activity

Chemical & Physical Properties

Related Compounds