Zaloglanstat

Names

[ Name ]:
Zaloglanstat

Biological Activity

[Description]:

Zaloglanstat (ISC-27864) is the inhibitor of the microsomal prostaglandin E synthase-1 (mPGES-1), and can be used to study asthma, osteoarthritis, rheumatoid arthritis, acute or chronic pain and neurodegenerative diseases, etc[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> PGE synthase

Research Areas >> Neurological Disease

[References]

[1]. Di Micco S, Terracciano S, Ruggiero D, Potenza M, Vaccaro MC, Fischer K, Werz O, Bruno I, Bifulco G. Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition. Front Chem. 2021 May 7;9:676631.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₂₀ClF₃N₄O₂

[ Molecular Weight ]:
452.86