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Dihydroevocarpine

Names

[ CAS No. ]:
15266-35-0

[ Name ]:
Dihydroevocarpine

[Synonym ]:
4(1H)-Quinolinone, 1-methyl-2-tridecyl-
1-Methyl-2-tridecyl-4(1H)-quinolinone

Biological Activity

[Description]:

Dihydroevocarpine induces cytotoxicity in acute myeloid leukemia via suppressing the mTORC1/2 activity[1].

[Related Catalog]:

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR
Research Areas >> Cancer

[References]

[1]. Zhang S, et al. Targeting of mTORC1/2 by dihydroevocarpine induces cytotoxicity in acute myeloid leukemia. J Cell Physiol. 2019;234(8):13032-13041.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
447.0±45.0 °C at 760 mmHg

[ Melting Point ]:
68-69℃

[ Molecular Formula ]:
C23H35NO

[ Molecular Weight ]:
341.53

[ Flash Point ]:
149.1±18.1 °C

[ Exact Mass ]:
341.271851

[ PSA ]:
22.00000

[ LogP ]:
8.22

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.514

Safety Information

[ Hazard Codes ]:
Xi