Tesidolumab
Names
[ CAS No. ]:
1531594-08-7
[ Name ]:
Tesidolumab
Biological Activity
[Description]:
Tesidolumab (LFG316) is a fully-human IgG1/λ anti-C5 monoclonal antibody of 143 kDa (without glycosylation). Tesidolumab (LFG316) blocks cleavage of C5 and prevents subsequent formation of the membrane attack complex[1].
[Related Catalog]:
[In Vitro]
Tesidolumab (LFG316) possesses a half-life in humans of approximately 9 days. Tesidolumab (LFG316) binds to a distinct epitope to that of eculizumab and ravulizumab, distant to Arg 885[1].
[References]
Chemical & Physical Properties
No Any Chemical & Physical Properties