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Amino-PEG9-alcohol

Names

[ CAS No. ]:
15332-95-3

[ Name ]:
Amino-PEG9-alcohol

Biological Activity

[Description]:

Amino-PEG9-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Sitterley KA, et al. Identification of Proprietary Amino Ethoxylates in Hydraulic Fracturing Wastewater Using Liquid Chromatography/Time-of-Flight Mass Spectrometry with Solid-Phase Extraction. Anal Chem. 2018 Sep 18;90(18):10927-10934.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H39NO9

[ Molecular Weight ]:
413.50

[ Storage condition ]:
2-8°C

Related Compounds