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Lanicemine

Names

[ CAS No. ]:
153322-05-5

[ Name ]:
Lanicemine

[Synonym ]:
UNII:9TMU325RK3
(S)-(+)-1-phenyl-2-(pyridin-2-yl)ethylamine
2-Pyridineethanamine, α-phenyl-, (αS)-
(1S)-1-Phenyl-2-(2-pyridinyl)ethanamine
9TMU325RK3
lanicemine
MFCD00924222

Biological Activity

[Description]:

Lanicemine (AZD6765) is a low-trapping NMDA channel blocker with a binding (Ki) of 0.56-2.1 μM[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> iGluR
Research Areas >> Neurological Disease
Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR

[Target]

NMDA Channel Blocker[1]


[References]

[1]. Sanacora G, et al. Lanicemine: a low-trapping NMDA channel blocker produces sustained antidepressant efficacywith minimal psychotomimetic adverse effects. Mol Psychiatry. 2014 Sep;19(9):978-85.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
307.7±27.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H14N2

[ Molecular Weight ]:
198.264

[ Flash Point ]:
160.6±10.8 °C

[ Exact Mass ]:
198.115692

[ LogP ]:
1.63

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.602

Related Compounds