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Autotaxin modulator 1

Names

[ CAS No. ]:
1548743-69-6

[ Name ]:
Autotaxin modulator 1

[Synonym ]:
8-{(1R)-1-[8-(Trifluoromethyl)-7-{[cis-4-(trifluoromethyl)cyclohexyl]oxy}-2-naphthyl]ethyl}-8-azabicyclo[3.2.1]octane-3-carboxylic acid
8-Azabicyclo[3.2.1]octane-3-carboxylic acid, 8-[(1R)-1-[8-(trifluoromethyl)-7-[[cis-4-(trifluoromethyl)cyclohexyl]oxy]-2-naphthalenyl]ethyl]-

Biological Activity

[Description]:

Autotaxin modulator 1 is a novel Autotaxin modulator extracted from Patent WO 2014018881 A1.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Research Areas >> Others

[References]

[1]. Guckian, Kevin, et al. Preparation of naphthalenes and isoquinolines as ATX modulating agents. WO 2014018881 A1 20140130.


[Related Small Molecules]

3-Isobutyl-1-methylxanthine | rolipram | PF-04957325 | AN-2728 | GLPG1690 | BAY-60-7550 | Icariin | Ibudilast | PF-8380 | TAK-063 | Dipyridamole | Cilostazol | GSK256066 | Cialis | Pentoxifylline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
586.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C28H31F6NO3

[ Molecular Weight ]:
543.541

[ Flash Point ]:
308.7±30.1 °C

[ Exact Mass ]:
543.220825

[ LogP ]:
6.25

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.544

[ Storage condition ]:
2-8℃

Related Compounds