Taltirelin acetate (TA-0910 acetate)

Names

[ Name ]:
Taltirelin acetate (TA-0910 acetate)

Biological Activity

[Description]:

Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Thyroid Hormone Receptor

Research Areas >> Neurological Disease

[Target]

IC50: 910 nM (Thyrotropin-releasing hormone receptor)[1]

[References]

[1]. Thirunarayanan N, et al. Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. Front Endocrinol (Lausanne). 2012 Oct 9;3:120.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₇N₇O₇

[ Molecular Weight ]:
465.46