m-PEG6-Tos

Names

[ CAS No. ]:
155887-96-0

[ Name ]:
m-PEG6-Tos

[Synonym ]:
MFCD22201542

Biological Activity

[Description]:

m-PEG6-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₃₄O₉S

[ Molecular Weight ]:
450.54

m-PEG6-Tos

Names

Biological Activity

Chemical & Physical Properties

Related Compounds