(S)-Ketoprofen trometamol

Names

[ Name ]:
(S)-Ketoprofen trometamol

[Synonym ]:
(2S)-2-(3-Benzoylphenyl)propanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (αS)-3-benzoyl-α-methylbenzeneacetate (salt)
Dexketoprofen trometamol
2-(3-Benzoylphenyl)propanoic acid - 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
Benzeneacetic acid, 3-benzoyl-α-methyl-, (αS)-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
Benzeneacetic acid, 3-benzoyl-α-methyl-, compd. with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1)
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, (S)-3-benzoyl-α-methylbenzeneacetate (salt)

Biological Activity

[Description]:

Dexketoprofen trometamol (Dexketoprofen tromethamine salt) is an orally active non-selective COX inhibitor. Dexketoprofen trometamol has a pain-relieving effect[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> COX

Research Areas >> Neurological Disease

[References]

[1]. Magdi Hanna, et al. A review of dexketoprofen trometamol in acute pain. Curr Med Res Opin. 2019 Feb;35(2):189-202.

Chemical & Physical Properties

[ Boiling Point ]:
431.3ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₅NO₆

[ Molecular Weight ]:
375.42

[ Flash Point ]:
228.8ºC

[ Exact Mass ]:
375.168182

[ PSA ]:
141.08000

[ LogP ]:
1.46680

[ Vapour Pressure ]:
3.32E-08mmHg at 25°C

Safety Information

[ HS Code ]:
2922199090

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%