3-Phenyl-1H-pyrazol-5-amine
Names
[ CAS No. ]:
1572-10-7
[ Name ]:
3-Phenyl-1H-pyrazol-5-amine
[Synonym ]:
MFCD00191749
1H-Pyrazol-3-amine, 5-phenyl-
1H-Pyrazol-5-amine, 3-phenyl-
3-Phenyl-1H-pyrazol-5-amine
3-Amino-5-phenylpyrazole
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
442.3±33.0 °C at 760 mmHg
[ Melting Point ]:
118-121ºC
[ Molecular Formula ]:
C9H9N3
[ Molecular Weight ]:
159.19
[ Flash Point ]:
251.5±12.6 °C
[ Exact Mass ]:
159.079651
[ PSA ]:
54.70000
[ LogP ]:
1.34
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.663
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ6109000
- CHEMICAL NAME :
- Pyrazole, 5-amino-3-phenyl-
- CAS REGISTRY NUMBER :
- 1572-10-7
- BEILSTEIN REFERENCE NO. :
- 0004947
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C9-H9-N3
- MOLECULAR WEIGHT :
- 159.21
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 630 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 27,295,1964
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UQ6109000
Precursor & DownStream
Precursor
DownStream
Articles
ChemMedChem 7(8) , 1453-64, (2012)
A library of new anthranilamide-pyrazolo[1,5-a]pyrimidine conjugates were designed, synthesized, and evaluated for their anticancer activity in cervical cancer cells such as HeLa and SiHa that possess...
Botulinum neurotoxin serotype A inhibitors: small-molecule mercaptoacetamide analogs.Bioorg. Med. Chem. 17(8) , 3072-9, (2009)
Botulinum neurotoxin elicits its paralytic activity through a zinc-dependant metalloprotease that cleaves proteins involved in neurotransmitter release. Currently, no drugs are available to reverse th...
An efficient one-step synthesis of heterobiaryl pyrazolo[3,4-b]pyridines via indole ring opening.Org. Lett. 11(22) , 5214-7, (2009)
A mild one-step synthetic method to access privileged heterobiaryl pyrazolo[3,4-b]pyridines from indole-3-carboxaldehyde derivatives and a variety of aminopyrazoles has been developed. This novel meth...