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BMS-986115

Names

[ CAS No. ]:
1584647-27-7

[ Name ]:
BMS-986115

Biological Activity

[Description]:

Notch inhibitor 1 is a potent Notch inhibitor, with IC50s of 7.8 and 8.5 nM for Notch 1 and Notch 3, respectively. Used in the research of cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Stem Cell/Wnt >> Notch

[Target]

IC50: 7.8 nM (Notch 1), 8.5 nM (Notch 3)[1]


[In Vitro]

Notch inhibitor 1 (Example 1) potently inhibits Notch signaling pathway[1].

[References]

[1]. Ashvinikumar V. Gavai, et al. Bis(fluoroalkyl)-1,4-benzodiazepinone compounds as notch inhibitors. WO2014047372A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H25F7N4O3

[ Molecular Weight ]:
574.49

Related Compounds