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MAGE-3 (271-279)

Names

[ CAS No. ]:
160295-81-8

[ Name ]:
MAGE-3 (271-279)

[Synonym ]:
L-Valine, L-phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-alanyl-L-leucyl-
L-Phenylalanyl-L-leucyl-L-tryptophylglycyl-L-prolyl-N-(diaminomethylene)-L-ornithyl-L-alanyl-L-leucyl-L-valine

Biological Activity

[Description]:

MAGE-3 (271-279) is a 271-279 residue peptide derived from melanoma antigens encoded by MAGE-3. MAGE-3 is a cytolytic T lymphocyte (CTL)-defined MAGE-3 protein associated with the human leukocyte antigen (HLA)-A2 molecule. MAGE-3 is overexpressed in different human tumor types, including malignant melanoma, but not by normal tissues except for testis and placenta[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. J Herman, et al. A peptide encoded by the human MAGE3 gene and presented by HLA-B44 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE3. Immunogenetics. 1996;43(6):377-83.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C53H79N13O10

[ Molecular Weight ]:
1058.276

[ Exact Mass ]:
1057.607300

[ PSA ]:
365.02000

[ LogP ]:
4.48

[ Index of Refraction ]:
1.642

Related Compounds