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HER2/neu (654-662) GP2

Names

[ CAS No. ]:
160790-21-6

[ Name ]:
HER2/neu (654-662) GP2

[Synonym ]:
iisavvgil
gp2

Biological Activity

[Description]:

HER2/neu (654-662) GP2 is a nine amino acid peptide derived from the human epidermal growth factor receptor 2 (HER2/nue, 654–662), induces HLA-A2-restricted cytotoxic T lymphocytes (CTL) reactive to various epithelial cancers[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Sun Y, et al. Observing the temperature dependent transition of the GP2 peptide using terahertz spectroscopy. PLoS One. 2012;7(11):e50306.

[2]. Tanaka Y, et al. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer. 2001 Nov;94(4):540-4.

Chemical & Physical Properties

[ Molecular Formula ]:
C42H77N9O11

[ Molecular Weight ]:
884.11

[ Exact Mass ]:
883.57400

[ PSA ]:
316.35000

[ LogP ]:
3.24420


Related Compounds