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Nrf2-IN-1

Names

[ CAS No. ]:
1610022-76-8

[ Name ]:
Nrf2-IN-1

Biological Activity

[Description]:

Nrf2-IN-1 (Compound 4f) is an inhibitor of nuclear factor-erythroid 2-related factor 2 (Nrf2), acts as a promising agent in acute myeloid leukemia (AML) therapy[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> NF-κB >> Keap1-Nrf2

[Target]

Nrf2[1]


[References]

[1]. Zhang J, et al. Discovery of a novel Nrf2 inhibitor that induces apoptosis of human acute myeloid leukemia cells. Oncotarget. 2017 Jan 31;8(5):7625-7636.

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22ClN3O2

[ Molecular Weight ]:
383.87

Related Compounds