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NSC636819

Names

[ CAS No. ]:
1618672-71-1

[ Name ]:
NSC636819

[Synonym ]:
Benzene, 1,5-bis[(E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitro-
1,5-Bis[(E)-2-(3,4-dichlorophenyl)vinyl]-2,4-dinitrobenzene
1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene

Biological Activity

[Description]:

NSC636819 is a competitive and selective inhibitor of KDM4A/KDM4B. KDM4A/KDM4B are potential progression factors for prostate cancer. NSC636819 has the potential for the research of cancer diseases, especially prostate cancer[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Epigenetics >> Histone Demethylase

[References]

[1]. Chu CH, et al. KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J Med Chem. 2014;57(14):5975-5985.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
625.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C22H12Cl4N2O4

[ Molecular Weight ]:
510.15

[ Flash Point ]:
332.1±31.5 °C

[ Exact Mass ]:
507.955109

[ LogP ]:
8.59

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.753

Related Compounds