GPR120 agonist 4x

Names

[ Name ]:
GPR120 agonist 4x

Biological Activity

[Description]:

GPR120 Agonist 1 is a potent and selective GPR120 agonist, and possesses promising antidiabetic effect and good safety profile to be a development candidate[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GPR120

Research Areas >> Metabolic Disease

[Target]

GPR120[1]

[In Vitro]

GPR120 Agonist 1 is a potent and selective GPR120 agonist. In GPR120 transfected HEK293 cells, GPR120 Agonist 1 displays good EC50 of 42 nM and 77 nM for human GPR120 and mouse GPR120 (the calcium flux assay), respectively[1].

[References]

[1]. Zhang X, et al. Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₂ClF₆NO₃S

[ Molecular Weight ]:
495.82

GPR120 agonist 4x

Names

Biological Activity

Chemical & Physical Properties

Related Compounds