Apalutamide D4

Names

[ Name ]:
Apalutamide D4

Biological Activity

[Description]:

Apalutamide D4 (ARN-509 D4) is a deuterium labeled Apalutamide. Apalutamide is a potent and competitive androgen receptor (AR) antagonist, binding AR with an IC50 of 16 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Androgen Receptor

[References]

[1]. Clegg NJ, et al. ARN-509: a novel antiandrogen for prostate cancer treatment. Cancer Res. 2012 Mar 15;72(6):1494-503.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₁H₁₁D₄F₄N₅O₂S

[ Molecular Weight ]:
481.46

Apalutamide D4

Names

Biological Activity

Chemical & Physical Properties

Related Compounds