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2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid

Names

[ CAS No. ]:
1657014-33-9

[ Name ]:
2-(4-Butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid

[Synonym ]:
2-(4-Butoxy-3-cyanophenyl)-4-methyl-5-thiazolecarboxylic acid

Biological Activity

[Description]:

Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a Ki of 0.6 nM[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Mayer MD, et al. Pharmacokinetics and pharmacodynamics of febuxostat, a new non-purine selective inhibitor of xanthine oxidase in subjects with renal impairment. Am J Ther. 2005;12(1):22-34.

Chemical & Physical Properties

[ Density]:
1.31±0.1 g/cm3 (20 ºC 760 Torr)

[ Molecular Formula ]:
C16H16N2O3S

[ Molecular Weight ]:
316.37

[ Water Solubility ]:
Insuluble (2.6E-3 g/L) (25 ºC)