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Glycosidase-IN-1

Names

[ CAS No. ]:
170376-12-2

[ Name ]:
Glycosidase-IN-1

Biological Activity

[Description]:

Glycosidase-IN-1 (Compound 9) is a glycosidase inhibitor synthesized from D-mannose. Glycosidase-IN-1 be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors. Glycosidase-IN-1 has hypoglycemic activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Metabolic Disease

[Target]

Glycosidase[1]


[In Vitro]

The synthesis of C5-mono-fluorinated piperidine iminosugar 3a commences with iminosugar Compound 8 that is prepared from D-mannose. In Scheme 2, protection of the ring nitrogen in Compound 8 using Boc-anhydride and Et3N gives Glycosidase-IN-1 (Compound 9)[1].

[References]

[1]. Naresh Bhuma, et al. Fluorinated piperidine iminosugars and their N-alkylated derivatives: Synthesis, conformational analysis, immunosuppressive and glycosidase inhibitory activity studies. Tetrahedron 74 (2018) 852-858.

Chemical & Physical Properties

[ Molecular Formula ]:
C13H23NO5

[ Molecular Weight ]:
273.33

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds