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T16A(inh)-C01

Names

[ CAS No. ]:
171506-87-9

[ Name ]:
T16A(inh)-C01

Biological Activity

[Description]:

T16A(inh)-C01 is an inhibitor of TMEM16A (ANO1). T16A(inh)-C01 blocks chloride channel mediated by ANO1 with an IC50 of 8.4 μM, without interfering with calcium signaling[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> Chloride Channel
Research Areas >> Others

[Target]

Target: Chloride Channel[1]


[References]

[1]. Namkung W, et al. TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells. J Biol Chem. 2011 Jan 21. 286(3):2365-74.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H16O5

[ Molecular Weight ]:
312.32

Related Compounds