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SB 202474

Names

[ CAS No. ]:
172747-50-1

[ Name ]:
SB 202474

[Synonym ]:
4-[5-Ethyl-2-(4-methoxyphenyl)-1H-imidazol-4-yl]pyridine
Pyridine, 4-[5-ethyl-2-(4-methoxyphenyl)-1H-imidazol-4-yl]-
SB 202474
MFCD06804624

Biological Activity

[Description]:

SB 202474, a negative analog of SB203580. SB 202474, which has no ability to inhibit p38 MAPK activity and is widely used as a negative control compound in p38 MAPK studies, also suppressed melanin synthesis induction[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Bellei B, et al. p38 regulates pigmentation via proteasomal degradation of tyrosinase. J Biol Chem. 2010;285(10):7288-7299.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
520.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H17N3O

[ Molecular Weight ]:
279.34

[ Flash Point ]:
183.9±20.4 °C

[ Exact Mass ]:
279.137177

[ LogP ]:
4.35

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.597

Related Compounds