3-[3-(DIMETHYLAMINO)PROPYL]-4-HYDROXY-N-[4-(4-PYRIDINYL)PHENYL]BENZAMIDE DIHYDROCHLORIDE

Names

[ Name ]:
3-[3-(DIMETHYLAMINO)PROPYL]-4-HYDROXY-N-[4-(4-PYRIDINYL)PHENYL]BENZAMIDE DIHYDROCHLORIDE

[Synonym ]:
3-[3-(dimethylamino)propyl]-4-hydroxy-N-(4-pyridin-4-ylphenyl)benzamide,hydrochloride
3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrobromide

Biological Activity

[Description]:

GR 55562 hydrochloride is a selective 5-HT1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Filip M, et al. Effects of serotonin (5-HT)(1B) receptor ligands, microinjected into accumbens subregions, on cocaine discrimination in rats. Naunyn Schmiedebergs Arch Pharmacol. 2002;366(3):226-234.

Chemical & Physical Properties

[ Density]:
1.192g/cm3

[ Boiling Point ]:
511.6ºC at 760 mmHg

[ Molecular Formula ]:
C₂₃H₂₆ClN₃O₂

[ Molecular Weight ]:
411.92

[ Flash Point ]:
263.2ºC

[ Exact Mass ]:
447.14800

[ PSA ]:
65.46000

[ LogP ]:
5.87770

[ Vapour Pressure ]:
4.36E-11mmHg at 25°C

[ Index of Refraction ]:
1.633

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22