MHI-148
Names
Biological Activity
[Description]:
MHI-148 is a near-infrared heptamethine cyanine dye with tumor-targeting properties for cancer detection, diagnosis and treatment. MHI-148 is immediately taken up and accumulated by lysosomes and mitochondria of tumor cells, but not in lysosomes and mitochondria of normal cells[1].
[Related Catalog]:
[In Vitro]
MHI-148 (10 µM, 1 h) is significantly more absorbed in HT-29 colon carcinoma cells than in normal NIH3T3 fibroblasts and has tumor imaging and targeting properties[1]. MHI-148 (0-1.5 µM, 3 days) causes only negligible toxicity in HT-29 and NIH3T3 cells[1].
Chemical & Physical Properties
[ Molecular Formula ]:
C42H52ClN2O4.Br
[ Molecular Weight ]:
764.24
Safety Information
[ Hazard Codes ]:
Xn