CYP1B1-IN-5

Names

[ CAS No. ]:
176442-56-1

[ Name ]:
CYP1B1-IN-5

[Description]:

CYP1B1-IN-5 (Compound 6q) is a potent and selective cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450

[Target]

CYP1B1:4.7 nM (IC50)

CYP1A1:190.7 nM (IC50)

CYP1A2:585.7 nM (IC50)

[In Vitro]

CYP1B1-IN-5 (Compound 6q) 通过与残基 Phe231、Phe134 和血红素形成 π-π 叠加相互作用，与 CYP1B1 的结合口袋结合[1]。

[References]

[ Molecular Formula ]:
C₁₄H₈INO₂

[ Molecular Weight ]:
349.12