(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin

Names

[ CAS No. ]:
176714-12-8

[ Name ]:
(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin

Biological Activity

[Description]:

(d(CH2)51,Tyr(Me)2,Dab5,Arg8)-Vasopressin (d(CH2)5[Tyr(Me)2, Dab5]AVP) is a specific antagonist of vasopressin V1a receptor, with a pA2 of 6.71[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> GPCR/G Protein >> Vasopressin Receptor

[References]

[1]. Chan WY, et, al. Discovery and design of novel and selective vasopressin and oxytocin agonists and antagonists: the role of bioassays. Exp Physiol. 2000 Mar;85 Spec No:7S-18S.  

Chemical & Physical Properties

[ Molecular Formula ]:
C52H76N14O11S2

[ Molecular Weight ]:
1137.38

Related Compounds