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4-Methylumbelliferyl butyrate

Names

[ CAS No. ]:
17695-46-4

[ Name ]:
4-Methylumbelliferyl butyrate

[Synonym ]:
(4-methyl-2-oxochromen-7-yl) butanoate
MFCD00038087
EINECS 241-694-7

Biological Activity

[Description]:

4-Methylumbelliferyl butyrate (4-MUB) is a coumarin-based fluorogenic substrate used for the identification of M. catarrhalis C4- esterase. 4-Methylumbelliferyl butyrate can converse to the blue-emissive 4-methylumbelliferone (4-MU; HY-N0187)[1].

[Related Catalog]:

Research Areas >> Others
Signaling Pathways >> Others >> Others

[References]

[1]. Uisung Lee, et al. Selective Butyrate Esterase Probe for the Rapid Colorimetric and Fluorogenic Identification of Moraxella catarrhalis. Anal Chem. 2020 Dec 15;92(24):16051-16057.  

Chemical & Physical Properties

[ Density]:
1.197 g/cm3

[ Boiling Point ]:
393.4ºC at 760 mmHg

[ Melting Point ]:
90-92ºC(lit.)

[ Molecular Formula ]:
C14H14O4

[ Molecular Weight ]:
246.25900

[ Flash Point ]:
199.8ºC

[ Exact Mass ]:
246.08900

[ PSA ]:
56.51000

[ LogP ]:
2.80690

[ Vapour Pressure ]:
2.13E-06mmHg at 25°C

[ Index of Refraction ]:
1.545

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
R26/27/28

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932209090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Rapid identification of Branhamella catarrhalis with 4-methylumbelliferyl butyrate.

J. Clin. Microbiol. 26 , 1227, (1988)

Branhamella catarrhalis can be distinguished from Neisseria spp. by the presence of butyrate esterase. This enzyme can be rapidly detected when 4-methylumbelliferyl butyrate is used as the substrate. ...

Characterization of an acidic cold-adapted cutinase from Thielavia terrestris and its application in flavor ester synthesis.

Food Chem. 188 , 439-45, (2015)

An acidic cutinase (TtcutB) from Thielavia terrestris CAU709 was purified to apparent homogeneity with 983 Um g(-1) specific activity. The molecular mass of the enzyme was estimated to be 27.3 and 27....

Fluorescence spectroscopic analysis of the structure and dynamics of Bacillus subtilis lipase A governing its activity profile under alkaline conditions.

Eur. Biophys. J. 44 , 655-65, (2015)

Because of their vast diversity of substrate specificity and reaction conditions, lipases are versatile materials for biocatalysis. Lipase A from Bacillus subtilis (BSLA) is the smallest lipase yet di...


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Related Compounds