NLRP3/AIM2-IN-3

Names

[ Name ]:
NLRP3/AIM2-IN-3

Biological Activity

[Description]:

NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of NLRP3 and AIM2 inflammatory bodies and has species differences. Its IC 50 value is 0.077 ± 0.008 μ M。

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

inhibitory activity against NLRP3 and AIM2:0.077±0.00 μM (IC50)

[References]

[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₄N₂O₂

[ Molecular Weight ]:
266.29

NLRP3/AIM2-IN-3

Names

Biological Activity

Chemical & Physical Properties

Related Compounds