E3 ligase Ligand-Linker Conjugates 4

E3 ligase Ligand-Linker Conjugates 4 is a synthesized compound that incorporates an E3 ligase ligand and a linker used in PROTAC technology.

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

Research Areas >> Others

E3 ligase Ligand-Linker Conjugates 4 together with JQ1 triggers the intracellular destruction of BET proteins[1].

[1]. Zengerle M, et al. Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4. ACS Chemical Biology (2015), 10(8), 1770-1777.

E3 ligase Ligand-Linker Conjugates 14 | E3 Ligase Ligand-Linker Conjugates 1 | E3 ligase Ligand-Linker Conjugates 17 | E3 ligase Ligand-Linker Conjugates 16 | (SRS)-AHPC-PEG3-NH2 hydrochloride | E3 ligase Ligand-Linker Conjugates 6 | E3 ligase Ligand-Linker Conjugates 18 | E3 Ligase Ligand-Linker Conjugates 2 | (SRS)-AHPC-PEG4-NH2 hydrochloride | E3 Ligase Ligand-Linker Conjugates 22 | E3 ligase Ligand-Linker Conjugates 10 | E3 ligase Ligand-Linker Conjugates 13 | E3 Ligase Ligand-Linker Conjugates 24 TFA | E3 ligase Ligand-Linker Conjugates 11