Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

Names

[ Name ]:
Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

Biological Activity

[Description]:

Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc can be used for the synthesis of PROTAC BET degrader[1]. (From patent WO2017180417A1 compound s7).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[Target]

Cereblon

[References]

[1]. Shaomeng Wang, et al. Bet protein degraders. WO2017180417A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₀H₄₂N₄O₁₁

[ Molecular Weight ]:
634.67

Thalidomide-O-amido-CH2-PEG3-CH2-NH-Boc

Names

Biological Activity

Chemical & Physical Properties

Related Compounds