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GNE-140 racemate

Names

[ CAS No. ]:
1802977-61-2

[ Name ]:
GNE-140 racemate

[Synonym ]:
2,4-Piperidinedione, 3-[(2-chlorophenyl)thio]-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-
3-[(2-Chlorophenyl)sulfanyl]-6-[4-(4-morpholinyl)phenyl]-6-(3-thienyl)-2,4-piperidinedione

Biological Activity

[Description]:

GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. (R)-GNE-140 is a potent lactate dehydrogenase A (LDHA) inhibitor.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Lactate Dehydrogenase
Research Areas >> Cancer

[Related Small Molecules]

GSK 2837808A | (R)-GNE-140 | LDH-IN-1 | FX-11 | Nifurtimox

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
739.0±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H23ClN2O3S2

[ Molecular Weight ]:
499.045

[ Flash Point ]:
400.7±32.9 °C

[ Exact Mass ]:
498.083862

[ LogP ]:
3.84

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.699

[ Storage condition ]:
2-8℃

Related Compounds