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endo-BCN-PEG4-Boc

Names

[ CAS No. ]:
1807501-83-2

[ Name ]:
endo-BCN-PEG4-Boc

[Synonym ]:
MFCD28505580
2,7,10,13,16-Pentaoxa-4-azanonadecan-19-oic acid, 1-[(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl]-3-oxo-, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 1-[(1R,8S,9s)-bicyclo[6.1.0]non-4-yn-9-yl]-3-oxo-2,7,10,13,16-pentaoxa-4-azanonadecan-19-oate

Biological Activity

[Description]:

endo-BCN-PEG4-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
594.3±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H43NO8

[ Molecular Weight ]:
497.621

[ Flash Point ]:
313.2±28.7 °C

[ Exact Mass ]:
497.298859

[ LogP ]:
2.41

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.506

Related Compounds