Ph-Bis(C1-N-(C2-NH-Boc)2)

Names

[ CAS No. ]:
1807521-06-7

[ Name ]:
Ph-Bis(C1-N-(C2-NH-Boc)2)

[Synonym ]:
MFCD28142457

Biological Activity

[Description]:

Ph-Bis(C1-N-(C2-NH-Boc)2) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl-Chain

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₆H₆₄N₆O₈

[ Molecular Weight ]:
708.93

Safety Information

[ Hazard Codes ]:
Xi

Ph-Bis(C1-N-(C2-NH-Boc)2)

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds