Mal-PEG1-PFP ester

Names

[ Name ]:
Mal-PEG1-PFP ester

[Synonym ]:
Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 2,3,4,5,6-pentafluorophenyl ester
MFCD26127800
Pentafluorophenyl 3-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoate

Biological Activity

[Description]:

Mal-PEG1-PFP ester is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
452.8±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₀F₅NO₅

[ Molecular Weight ]:
379.236

[ Flash Point ]:
227.7±28.7 °C

[ Exact Mass ]:
379.047913

[ LogP ]:
2.36

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.506

[ Storage condition ]:
2-8°C

Mal-PEG1-PFP ester

Names

Biological Activity

Chemical & Physical Properties

Related Compounds