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2-hydroxyethyl disulfide mono-Tosylate

Names

[ CAS No. ]:
1807530-16-0

[ Name ]:
2-hydroxyethyl disulfide mono-Tosylate

Biological Activity

[Description]:

2-Hydroxyethyl disulfide mono-tosylate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C11H16O4S3

[ Molecular Weight ]:
308.44

Related Compounds