4-methylumbelliferyl heptanoate

Names

[ Name ]:
4-methylumbelliferyl heptanoate

[Synonym ]:
Heptanoic acid 4-methylumbelliferyl ester
4-Methylumbelliferyl enanthate
4-Methyl-umbelliferon-heptanoat
4-methyl-2-oxo-2H-1-benzopyran-7-yl heptanoate
EINECS 242-207-0
4-Methylumbelliferone heptanoate
4-Methylumbelliferyl heptanoate
Heptanoic acid,4-methyl-2-oxo-2H-1-benzopyran-7-yl ester
7-heptanoyloxy-4-methyl-chromen-2-one
4-methyl-2-oxo-2h-chromen-7-yl heptanoate
MFCD00037611
4-Methylumbelliferyl enanthate Heptanoic acid 4-methylumbelliferyl ester

Biological Activity

[Description]:

4-Methylumbelliferyl heptanoate is a potent fluorometric substrate of lipase[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Guilbault, G. G., et al. N-Methyl Indoxyl Esters As Fluorometric Substrates For Lipase. Analytical Letters, 2(4), 185–196.

Chemical & Physical Properties

[ Density]:
1.129g/cm3

[ Boiling Point ]:
429ºC at 760mmHg

[ Melting Point ]:
41-42 °C(lit.)

[ Molecular Formula ]:
C₁₇H₂₀O₄

[ Molecular Weight ]:
288.33800

[ Flash Point ]:
214.5ºC

[ Exact Mass ]:
288.13600

[ PSA ]:
56.51000

[ LogP ]:
3.97720

[ Vapour Pressure ]:
1.45E-07mmHg at 25°C

[ Index of Refraction ]:
1.531

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2932209090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932209090

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Concurrent MEK and autophagy inhibition is required to restore cell death associated danger-signalling in Vemurafenib-resistant melanoma cells.

Biochem. Pharmacol. 93(3) , 290-304, (2015)

Vemurafenib (PLX4032), an inhibitor of BRAF(V600E), has demonstrated significant clinical anti-melanoma effects. However, the majority of treated patients develop resistance, due to a variety of molec...

A lipid switch unlocks Parkinson's disease-associated ATP13A2.

Proc. Natl. Acad. Sci. U. S. A. 112 , 9040-5, (2015)

ATP13A2 is a lysosomal P-type transport ATPase that has been implicated in Kufor-Rakeb syndrome and Parkinson's disease (PD), providing protection against α-synuclein, Mn(2+), and Zn(2+) toxicity in v...

Rapid detection of total and fecal coliforms in water by enzymatic hydrolysis of 4-methylumbelliferone-beta-D-galactoside.

Appl. Environ. Microbiol. 54(8) , 2118-22, (1988)

Three fluorogenic methylumbelliferone (MU) substrates were evaluated for rapid detection of total and fecal coliform bacteria (TC and FC) in drinking water. 4-MU-beta-D-galactoside, MU-heptanoate, and...