Guanylin(human)

Names

[ Name ]:
Guanylin(human)

[Synonym ]:
h-pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys-oh
pro-gly-thr-cys-glu-ile-cys-ala-tyr-ala-ala-cys-thr-gly-cys
PGTCEICAYAACTGC

Biological Activity

[Description]:

Guanylin(human), a 15-amino acid peptide, is an endogenous intestinal guanylate cyclase activator. Guanylin(human) is mainly found in gastrointestinal tract which regulates electrolytead water transport in intestinal and renal epithelia through cyclic GMP-dependent mechanism[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Endocrinology

Signaling Pathways >> GPCR/G Protein >> Guanylate Cyclase

[References]

[1]. M G Currie, et al. Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):947-51.

[2]. J Bełtowski. Guanylin and related peptides. J Physiol Pharmacol. 2001 Sep;52(3):351-75.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₈H₈₇N₁₅O₂₁S₄

[ Molecular Weight ]:
1458.66000

[ Exact Mass ]:
1457.51000

[ PSA ]:
655.92000

Guanylin(human)

Names

Biological Activity

Chemical & Physical Properties

Related Compounds