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Sodium houttuyfonate

Names

[ CAS No. ]:
1847-58-1

[ Name ]:
Sodium houttuyfonate

[Synonym ]:
Dodecyloxycarbonylmethanesulfonic acid sodium salt
Dodecyl sodium sulfoacetate
Sodium lauryl sulfoacetate
Acetic acid, 2-sulfo-, dodecyl ester, sodium salt (1:1)
Sodium 2-(dodecyloxy)-2-oxoethanesulfonate
2-Sulfoacetic acid dodecyl ester sodium salt

Biological Activity

[Description]:

Sodium lauryl sulfoacetate is a solid anionic surfactant of vegetable origin[1]. Sodium lauryl sulfoacetate is an immunoadjuvant. Anti-immunosuppressive effect[2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Tiffany Ann Renninger. Encapsulated dehydrated shampoo comprising sodium lauryl sulfoacetate. US10357095B1.

[2]. Cheng D, et al. The immune enhancement of sodium lauryl sulfoacetate in chickens. Vet Med Int. 2010;2010:485060.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H27NaO5S

[ Molecular Weight ]:
330.416

[ Exact Mass ]:
330.147675

[ PSA ]:
91.88000

[ LogP ]:
4.07650

[ Storage condition ]:
2-8C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AJ4930000
CHEMICAL NAME :
Acetic acid, sulfo-, 1-dodecyl ester, sodium salt
CAS REGISTRY NUMBER :
1847-58-1
LAST UPDATED :
199701
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C14-H27-O5-S.Na
MOLECULAR WEIGHT :
330.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
980 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JADSAY Journal of the American Dental Association. (American Dental Assoc., 211 E. Chicago Ave., Chicago, IL 60611) V.9- 1922- Volume(issue)/page/year: 26,1461,1939 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
22400 mg/kg/28D-I
TOXIC EFFECTS :
Brain and Coverings - changes in brain weight Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(3),261,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83141 No. of Facilities: 47 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 990 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83141 No. of Facilities: 304 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 3648 (estimated) No. of Female Employees: 3648 (estimated)

Safety Information

[ HS Code ]:
2914509090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%


Related Compounds