2-azidoacetic acid

Names

[ Name ]:
2-azidoacetic acid

[Synonym ]:
azidoglycine
Acetic acid,2-azido
azido acetic acid
Triazidoacetic acid

Biological Activity

[Description]:

Azidoacetic Acid (2-Azidoacetic acid) (compound 92-1) is a click chemistry reagent containing an azide group. Azidoacetic Acid can be used as a small molecule tool for the synthesis of PROTAC[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Ma Xin et al. Class of novel Smad3 protein degraders and application. Patent WO2022148459A1.

Chemical & Physical Properties

[ Boiling Point ]:
98-100ºC 0,1mm

[ Melting Point ]:
13-15ºC

[ Molecular Formula ]:
C₂H₃N₃O₂

[ Molecular Weight ]:
101.06400

[ Exact Mass ]:
101.02300

[ PSA ]:
87.05000

[ Index of Refraction ]:
1.47

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R2

[ Safety Phrases ]:
26-36/37/39

[ RIDADR ]:
UN 1993

[ HS Code ]:
2929909090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2929909090

[ Summary ]:
2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Mass spectrometric analysis of products of metabolic glycan engineering with azido-modification of sialic acids.

Anal. Bioanal. Chem 407 , 8945-58, (2015)

Metabolic engineering of glycans present on antibodies and other glycoproteins is becoming an interesting research area for improving our understanding of the glycome. With knowledge of the sialic aci...