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2B-(SP) (TFA)

Names

[ CAS No. ]:
186901-17-7

[ Name ]:
2B-(SP) (TFA)

[Synonym ]:
m.w. 1835.88 c71h123n26o29p

Biological Activity

[Description]:

2B-(SP) is a eIF2B-based substrate for glycogen synthase kinase-3 (GSK-3). 2B-(SP) is readily phosphorylated by both the α and β isoforms of GSK-3[1].

[Related Catalog]:

Signaling Pathways >> Stem Cell/Wnt >> GSK-3
Research Areas >> Neurological Disease
Signaling Pathways >> PI3K/Akt/mTOR >> GSK-3

[Target]

GSK-3α

GSK-3β


[References]

[1]. G I Welsh, et al. Peptide substrates suitable for assaying glycogen synthase kinase-3 in crude cell extracts.Anal Biochem. 1997 Jan 1;244(1):16-21.

Chemical & Physical Properties

[ Molecular Formula ]:
C71H123N26O29P

[ Molecular Weight ]:
1835.87000

[ Exact Mass ]:
1834.87000

[ PSA ]:
928.52000


Related Compounds