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(Tyr0)-Urocortin (rat)

Names

[ CAS No. ]:
187111-93-9

[ Name ]:
(Tyr0)-Urocortin (rat)

[Synonym ]:
(TYR0)-UROCORTIN (RAT)

Biological Activity

[Description]:

(Tyr0)-Urocortin, rat is a high-affinity agonist of corticotropin-releasing factor receptor type 1 (CRF-R1) and type 2 (CRF-R2). (Tyr0)-Urocortin, rat shows inhibitory binding constants (Ki) of 1-2 nM[1].

[Related Catalog]:

Research Areas >> Endocrinology
Signaling Pathways >> GPCR/G Protein >> CRFR

[Target]

CRFR1

CRFR2


[References]

[1]. Perrin MH, et al. Comparison of an agonist, urocortin, and an antagonist, astressin, as radioligands for characterization of corticotropin-releasing factor receptors. J Pharmacol Exp Ther. 1999 Feb;288(2):729-34.  

Chemical & Physical Properties

[ Appearance of Characters ]:
lyophilized powder (hygroscopic)

[ Storage condition ]:
−20°C

Safety Information

[ WGK Germany ]:
3

Related Compounds