KDM5A-IN-1

Names

[ CAS No. ]:
1905481-36-8

[ Name ]:
KDM5A-IN-1

[Synonym ]:
Cyclopropanecarboxamide, N-[(3R)-1-[[3-(1-methylethyl)-1H-pyrazol-5-yl]carbonyl]-3-pyrrolidinyl]-
N-{(3R)-1-[(3-Isopropyl-1H-pyrazol-5-yl)carbonyl]-3-pyrrolidinyl}cyclopropanecarboxamide

Biological Activity

[Description]:

KDM5A-IN-1 is an inhibitor histone demethylases. Target: Histone Demethylase

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Histone Demethylase

Research Areas >> Cancer

[References]

[1]. Kwong Wah LAI, et al. Pyrrolidine amide compounds as histone demethylase inhibitors. PCT Int. Appl. (2016), WO 2016057924 A1 20160414.

[Related Small Molecules]

GSK-J4 | QC6352 | GSK2879552 | SP-2509 | CPI-455 | trans-2-Phenylcyclopropylamine hemisulfate salt | 5-Carboxy-8-hydroxyquinoline | ML324 | GSK-LSD1 Dihydrochloride | NCGC00244536 | Daminozide | ORY-1001(trans) | JIB-04 | AS 8351 | KDM5-IN-1

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
592.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₂₂N₄O₂

[ Molecular Weight ]:
290.361

[ Flash Point ]:
312.2±30.1 °C

[ Exact Mass ]:
290.174286

[ LogP ]:
-1.13

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.586

[ Storage condition ]:
2-8℃

KDM5A-IN-1

Names

Biological Activity

Chemical & Physical Properties

Related Compounds