Salvigenin

Names

[ CAS No. ]:
19103-54-9

[ Name ]:
Salvigenin

[Synonym ]:
5-Hydroxy-6,7,4'-trimethoxyflavone
5-Hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
salvigenin
5-Hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
5-Hydroxy-4',6,7-trimethoxyflavone
Psathyrotin
5-hydroxyl-4',6,7-trimethoxylflavone
4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-(4-methoxyphenyl)-
6,7,4'-trimethylscutellarein

Biological Activity

[Description]:

Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Autophagy >> Autophagy

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[References]

[1]. Rafatian G, et al. Increase of autophagy and attenuation of apoptosis by Salvigenin promote survival of SH-SY5Y cells following treatment with H₂O₂. Mol Cell Biochem. 2012 Dec;371(1-2):9-22.

[2]. Noori S, et al. Antitumor and immunomodulatory effects of salvigenin on tumor bearing mice. Cell Immunol. 2013 Nov-Dec;286(1-2):16-21.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
535.9±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₈H₁₆O₆

[ Molecular Weight ]:
328.316

[ Flash Point ]:
196.9±23.6 °C

[ Exact Mass ]:
328.094696

[ PSA ]:
78.13000

[ LogP ]:
3.01

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.606

[ Storage condition ]:
2-8℃

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%