Anti-virus agent 1
Names
[ CAS No. ]:
1911578-83-0
[ Name ]:
Anti-virus agent 1
Biological Activity
[Description]:
Anti-virus agent 1 (compound 4i), a phosphoramidate prodrug of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV)[1][2].
[Related Catalog]:
[In Vitro]
Anti-virus agent 1 (compound 4i) has antiviral activity for EBOV in HeLa cell (EC50=1845 nM), HMVEC cell (TERT-immortalized human foreskin microvascular endothelial cells; ATCC-4025; EC50=367 nM), human macrophages (EC50=297 nM). Anti-virus agent 1 has a CC50 of 21 μM in MT4 cell (human leukemia T-cell)[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C24H29N6O8P
[ Molecular Weight ]:
560.50