H-Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL)-OH

Names

[ CAS No. ]:
1914987-47-5

[ Name ]:
H-Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL)-OH

[Synonym ]:
N-({5-[(2-Aminoethyl)amino]-1-naphthyl}sulfonyl)-L-α-glutamyl-L-prolyl-L-leucyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-arginyl-N-(4-{(E)-[4-(dimethylamino)phenyl]diazenyl}benzoyl)-L-lysine
L-Lysine, N-[[5-[(2-aminoethyl)amino]-1-naphthalenyl]sulfonyl]-L-α-glutamyl-L-prolyl-L-leucyl-L-phenylalanyl-L-alanyl-L-α-glutamyl-L-arginyl-N-[4-[(E)-2-[4-(dimethylamino)phenyl]diazenyl]be 
nzoyl]-

Biological Activity

[Description]:

Glu(EDANS)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(DABCYL) is a calpain substrate. The excitation wavelength is 380 nm and the emission wavelength is 500 nm for Glu(Edans)-Pro-Leu-Phe-Ala-Glu-Arg-Lys(Dabcyl)[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Jo H, et al. Development of α-helical calpain probes by mimicking a natural protein-protein interaction. J Am Chem Soc. 2012 Oct 24;134(42):17704-13.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₇₂H₉₇N₁₇O₁₆S

[ Molecular Weight ]:
1488.710

[ Exact Mass ]:
1487.702026

[ LogP ]:
4.59

[ Index of Refraction ]:
1.658