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Zeylenone

Names

[ CAS No. ]:
193410-84-3

[ Name ]:
Zeylenone

[Synonym ]:
2-Cyclohexen-1-one, 4-(benzoyloxy)-6-[(benzoyloxy)methyl]-5,6-dihydroxy-, (4R,5S,6S)-
[(1S,5R,6S)-5-(Benzoyloxy)-1,6-dihydroxy-2-oxo-3-cyclohexen-1-yl]methyl benzoate

Biological Activity

[Description]:

Zeylenone, isolated from ethanol extract of the leaves of Uvaria grandiflora Roxb. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis
Research Areas >> Cancer

[References]

[1]. Zhang L, et al. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Sci Rep. 2017 May 10;7(1):1669.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
569.6±50.0 °C at 760 mmHg

[ Melting Point ]:
150-152℃

[ Molecular Formula ]:
C21H18O7

[ Molecular Weight ]:
382.363

[ Flash Point ]:
201.4±23.6 °C

[ Exact Mass ]:
382.105255

[ PSA ]:
110.13000

[ LogP ]:
3.78

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.642

Related Compounds