[5-(2-THIENYL)-3-ISOXAZOLYL]METHANOL

Names

[ CAS No. ]:
194491-44-6

[ Name ]:
[5-(2-THIENYL)-3-ISOXAZOLYL]METHANOL

[Synonym ]:
4b0j
F2135-0540
3MQ

Biological Activity

[Description]:

[5-(2-Thienyl)-3-isoxazolyl]methanol (Compound D) is an AgrA-DNA binding inhibitor. [5-(2-Thienyl)-3-isoxazolyl]methanol can be used for S.aureus infection research[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Leonard PG, et al. Identification of a hydrophobic cleft in the LytTR domain of AgrA as a locus for small molecule interactions that inhibit DNA binding. Biochemistry. 2012 Dec 18;51(50):10035-43.

Chemical & Physical Properties

[ Density]:
1.351g/cm3

[ Boiling Point ]:
366ºC at 760mmHg

[ Melting Point ]:
54-55ºC

[ Molecular Formula ]:
C₈H₇NO₂S

[ Molecular Weight ]:
181.21

[ Exact Mass ]:
181.02000

[ PSA ]:
74.50000

[ LogP ]:
1.89540

[ Vapour Pressure ]:
5.3E-06mmHg at 25°C

[ Index of Refraction ]:
1.603

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S24/25

[ HS Code ]:
2934999090

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%