(1S,3R)-GNE-502

Names

[ CAS No. ]:
1953134-15-0

[ Name ]:
(1S,3R)-GNE-502

Biological Activity

[Description]:

(1S,3R)-GNE-502 (compound 179) is a potent ERα degrader with an EC50 value of 13 nM against ERα in MCF7 HCS. (1S,3R)-GNE-502 can be used to research cancer related with estrogen receptor[1].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR

Research Areas >> Cancer

[Target]

ERα:13 nM (EC50)

[References]

[1]. Simon Charles Goodacre, et al. Tetrahydro-Pyrido[3,4-b]Indole Estrogen Receptor Modulators And Uses Thereof. WO2016097072A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₃₀FN₃O₃S

[ Molecular Weight ]:
471.59

(1S,3R)-GNE-502

Names

Biological Activity

Chemical & Physical Properties

Related Compounds