Acetyl-Neurotrophin Receptor (368-381) amide (human)

Names

[ CAS No. ]:
197230-90-3

[ Name ]:
Acetyl-Neurotrophin Receptor (368-381) amide (human)

[Synonym ]:
m.w. 1565.86 c69h124n22o19
ac-ala-thr-leu-asp-ala-leu-leu-ala-ala-leu-arg-arg-ile-gln-nh2

Biological Activity

[Description]:

NTR 368 is a peptide derived from p75 neurotrophin receptor (p75NTR) corresponding to residues 368-381 of the human receptor. NTR 368 has helix forming propensity in the presence of micellar lipid. NTR 368 is a potent inducer of neural apoptosis[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Neurological Disease

[References]

[1]. M R Hileman, et al. A cytoplasmic peptide of the neurotrophin receptor p75NTR: induction of apoptosis and NMR determined helical conformation. FEBS Lett. 1997 Sep 29;415(2):145-54.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₉H₁₂₄N₂₂O₁₉

[ Molecular Weight ]:
1565.86000

[ Exact Mass ]:
1564.94000

[ PSA ]:
674.91000

[ LogP ]:
3.49150