Aranotine

Names

[ CAS No. ]:
19885-51-9

[ Name ]:
Aranotine

[Synonym ]:
(7aR)-5t-acetoxy-13t-hydroxy-(5at,13at)-5,5a,13,13a-tetrahydro-8H,16H-7ar,15ac-epidisulfano-bis(oxepino[3',4':4,5]pyrrolo)[1,2-a,1',2'-d]pyrazine-7,15-dione
Aranotine [INN-French]
Ariotin
Aranotina [INN-Spanish]
Aranotinum [INN-Latin]

Biological Activity

[Description]:

Aranotin strongly binds to Nsp15 viral protein. Aranotin can be used as promising SARS-CoV-2 replication strong inhibitor. Aranotin has the potential for COVID-19 research[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> SARS-CoV

[References]

[1]. Suresh Kumar, et al. Identification of phytochemicals as potential therapeutic agents that binds to Nsp15 protein target of coronavirus (SARS-CoV-2) that are capable of inhibiting virus replication. Phytomedicine. 2021 May:85:153317.

Chemical & Physical Properties

[ Density]:
1.72g/cm3

[ Boiling Point ]:
853.6ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₈N₂O₇S₂

[ Molecular Weight ]:
462.49600

[ Flash Point ]:
470.1ºC

[ Exact Mass ]:
462.05600

[ PSA ]:
156.21000

[ LogP ]:
1.01340

[ Vapour Pressure ]:
6.39E-34mmHg at 25°C

[ Index of Refraction ]:
1.781

Safety Information

[ RIDADR ]:
UN 1544

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Aranotine

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Related Compounds